The Endocannabinoid System and Medical Cannabis – An Introduction

This module explores the endocannabinoid system (ECS) and its critical role in the effects of medical cannabis. It examines the discoveries that shaped our understanding of the ECS, its primary components—such as CB1, CB2, and TRPV1 receptors—and the mechanisms of retrograde cell signaling, which underpins how cannabinoids influence physiological processes.

Participants will learn about the role of ECS ligands and non-ligand mediators in cannabis pharmacology, the concept of endocannabinoid tone, and factors that can affect it.

Clinical considerations are addressed to provide a deeper understanding of how the ECS informs the safe and effective use of medical cannabis in patient care.

Preview this module by watching the video above.

Estimated Duration: 1 hour

Access Duration: 12 months from date of purchase

Upon completion of this module, you’ll be able to:

• Describe the discoveries that shaped today's understanding of the endocannabinoid system (ECS)
• Explain the functions of the ECS, its main components, and how they interact
• Discuss the function and benefits of retrograde cell signalling
• Outline the roles and functions of cannabinoid receptors CB1 and CB2, and vanilloid receptor TRPV1
• Identify ECS ligands and non-ligand mediators and describe their role in ECS function
• Define endocannabinoid tone and its influencing factors
• Discuss clinical considerations related to the ECS